Possibly, though under some certain very specific conditions.  Marvel Studios has regained the rights to use characters like Blade, Ghost Rider, Daredevil and The Punisher, though Fox owns not only the rights to use the X-Men in features (which Wolverine is a member) but also the term “mutants” – describing enhanced human beings – as well.

And speaking of Daredevil, I suspect that a similar fate was only just avoided with The Fantastic Four, which was rushed into production with Josh Trask (Chronicle) at the helm.

Since Wolverine doesn’t necessarily “exist” outside the X-Men continuity, I suspect that for Marvel to regain the rights to the character they would have to first gain the rights to the entire X-Universe of characters.

And that’s possible, though considering how successful the last X-Men film was, it’s very, very unlikely.

What’s more likely – if Wolverine’s performance overseas were weaker or grows weaker overall – is that we would see no more single X-Men adventures, and instead concentrate on the team as a whole.